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Harnessing Genomics for Disease Resistance in Cucumbers, Melons and Squashes | Scientia

May 20, 2019July 14, 2021 cuccap Featured Articles

Through genomic studies collaborators in the CucCAP project aim to bring disease-resistant cucumbers, melons, squash and watermelon to farmers and hence ensure greater food sustainability into the future.

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Featured Article

CucCAP scientists identify markers for powdery mildew resistance in watermelon

Powdery mildew outbreaks, caused by Podosphaera xanthii, cause reduced yields and fruit quality in watermelon. CucCAP scientists at Clemson University and the USDA Vegetable Laboratory Charleston SC employed a bulked segregant analysis approach using data from 1147 accessions from the USDA Citrullus germplasm collection to perform an extreme-phenotype genome-wide association study (XP-GWAS) of tolerance to P. xanthii race 2W. Kompetitive Allele-Specific PCR (KASP) markers were designed for significant SNPs associated with reduced disease. The best marker in each region explained 21-31% of the variation in powdery mildew tolerance.

For further reading:

Branham et al., 2025. Extreme-phenotype genome-wide association study (XP-GWAS) of powdery mildew race 2 W tolerance in the USDA Citrullus germplasm collection. Scientific Reports. DOI10.1038/s41598-025-89445-8

 

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USDA National Institute of Food and Agriculture U.S. DEPARTMENT OF AGRICULTURE

The Cucurbit Coordinated Agricultural Project (CucCAP) is a USDA-National Institute of Food and Agriculture Specialty Crop Research Initiative grant under award number
2020-51181-32139.

Cooperating Institutions:

Boyce Thompson Institute; Cornell University; Michigan State University; North Carolina State University; Clemson University; University of Puerto Rico; University of Wisconsin; University of Florida; University of Georgia; West Virginia State University; U.S. Department of Agriculture, Agricultural Research Service

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